Product Overview
Balixafortide TFA (1051366-32-5 free base) | TP2141 | TargetMol Chemicals
CAS: TP2141
Smiles:
Formula: C82H113N22F3O23S2
Pathway: Autophagy|||GPCR/G Protein|||Immunology/Inflammation
Target: CXCR
Receptor: N/A
Bioactivity: Balixafortide TFA (POL6326 TFA) is a selective, well-tolerated peptidic CXCR4 antagonist (IC50 < 10 nM). It shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux (IC50s < 10 nM).
Molecular Weight: 1896, 05
