Product Overview
Barbadin | T14498 | TargetMol Chemicals
CAS: 356568-70-2
Smiles: Nn1cnc2scc(-c3ccc(Cc4ccccc4)cc3)c2c1=O
Formula: C19H15N3OS
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor. It has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors[1].
Molecular Weight: 333, 41