Product Overview
BAY 60-6583 | T14506 | TargetMol Chemicals
CAS: 910487-58-0
Smiles: NC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC3CC3)cc2)c1C#N
Formula: C19H17N5O2S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: BAY 60-6583 is a potent and high-affinity agonist of adenosine A2B receptor (EC50 = 3 nM) over A1, A2A, and A3 receptors and it has a cardioprotective effect in a myocardial ischemia model[1][5]. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with Ki values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model[1][5].
Molecular Weight: 379, 44
