Product Overview
BBR 2160 | T26751 | TargetMol Chemicals
CAS: 118587-22-7
Smiles: CCOC(=O)C1=C(CSCCNC=O)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC
Formula: C21H25N3O7S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on guinea-pig papillary muscle and sheep Purkinje fibres. BBR 2160 (10(-7) and 10(-6) M) dose dependently decreased the contractility of driven papillary muscle and Purkinje fibre. This effect was associated with a lowering of the plateau phase and a shortening of action potential duration in papillary muscle.
Molecular Weight: 463, 51
