Product Overview
BDA-366 | T6778 | TargetMol Chemicals
CAS: 1909226-00-1
Smiles:
Formula: C24H29N3O4
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: BDA-366 is a potent Bcl2 antagonist, binding Bcl2-BH4 domain with high affinity and selectivity (Ki = 3.3 nM). BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells[1].
Molecular Weight: 423, 5
