Product Overview
Belizatinib | T4257 | TargetMol Chemicals
CAS: 1357920-84-3
Smiles: CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12
Formula: C33H44FN5O3
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: Trk receptor|||ALK
Receptor: N/A
Bioactivity: Belizatinib is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.
Molecular Weight: 577, 75