Product Overview
Belzutifan | T16679 | TargetMol Chemicals
CAS: 1672668-24-4
Smiles: CS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2[C@@H](F)[C@@H](F)[C@@H](O)c12
Formula: C17H12F3NO4S
Pathway: Angiogenesis|||Chromatin/Epigenetic
Target: HIF
Receptor: N/A
Bioactivity: PT2977 is a potential treatment for clear cell renal cell carcinoma (ccRCC). PT2977 is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). PT2977, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
Molecular Weight: 383, 34