Product Overview
Bencycloquidium Bromide | T26770 | TargetMol Chemicals
CAS: 860804-18-8
Smiles: [Br-].C[N+]12CCC(CC1)C(C2)OCC(O)(C1CCCC1)c1ccccc1
Formula: C21H32BrNO2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M(3) receptor in Chinese hamster ovary (CHO) cells (M(1) pKi=7.86, M(2) pKi=7.21, M(3) pKi=8.21); pA(2)=8.85, 8.71 and 8.57 in methacholine-induced contraction of trachea, ileum and urinary bladder, 8.19 in methacholine-induced bradycardia of right atrium in vitro, respectively.
Molecular Weight: 410, 396
