Product Overview
Beta-Hydroxyisovalerylshikonin | TN1440 | TargetMol Chemicals
CAS: 7415-78-3
Smiles: CC(C)=CC[C@@H](OC(=O)CC(C)(C)O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
Formula: C21H24O7
Pathway: Angiogenesis|||GPCR/G Protein|||Immunology/Inflammation|||JAK/STAT signaling|||Metabolism|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||Tyrosine Kinases|||Prostaglandin Receptor|||Src|||AMPK|||Fatty Acid Synthase
Receptor: N/A
Bioactivity: Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly decreased viability of HCT116 cells (IC50 values = 30.9 μg/mL).
Molecular Weight: 388, 416
