Product Overview
BF-1 | T26781 | TargetMol Chemicals
CAS: 518980-66-0
Smiles: CCOc1ccc2C(=C3CCN(C)CC3)c3c(OC)cccc3Sc2c1
Formula: C22H25NO2S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BF-1 is a 5-Hydroxytryptamine receptor 2B antagonist. BF-1 was tested as potential migraine prophylactic drug by blocking BW723C86 (5-((thiophen-2-yl)methoxy)-α-methyltryptamine) or meta-chlorophenylpiperazine (mCPP) induced neurogenic dural plasma protein extravasation in a guinea pig model that may resemble a migraine attack.
Molecular Weight: 367, 51
