Product Overview
BGG463 | T4618 | TargetMol Chemicals
CAS: 890129-26-7
Smiles: CN1CCN(Cc2ccc(NC(=O)c3cccc4cc(Oc5cc(NC(C)=O)ncn5)ccc34)cc2C(F)(F)F)CC1
Formula: C30H29F3N6O3
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: Bcr-Abl|||CDK
Receptor: N/A
Bioactivity: BGG463 can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.
Molecular Weight: 578, 596