Product Overview
BH3I-2' | T26789 | TargetMol Chemicals
CAS: 315195-18-7
Smiles: Oc1c(I)cc(Cl)cc1C(=O)Nc1cc(ccc1Cl)S(=O)(=O)c1ccc(Cl)cc1
Formula: C19H11Cl3INO4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3 by targeting the Bcl-x binding pocket.
Molecular Weight: 582, 61
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