Product Overview
BI-0252 | T14554 | TargetMol Chemicals
CAS: 1818291-27-8
Smiles: OC(=O)c1ccc(cc1)[C@H]1C[C@H]2[C@@H](N1)[C@H](c1cccc(Cl)c1F)[C@@]1(N2CC2CC2)C(=O)Nc2cc(Cl)ccc12
Formula: C30H26Cl2FN3O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.
Molecular Weight: 566, 45
