Product Overview
BI 2536 | T6173 | TargetMol Chemicals
CAS: 755038-02-9
Smiles: CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O
Formula: C28H39N7O3
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Target: Apoptosis|||Epigenetic Reader Domain|||PLK
Receptor: N/A
Bioactivity: BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.
Molecular Weight: 521, 66
