Product Overview
BI-3802 | T5408 | TargetMol Chemicals
CAS: 2166387-65-9
Smiles: CNC(=O)COc1cc2cc(Nc3nc(ncc3Cl)N3C[C@@H](C)C[C@@H](C)C3)ccc2n(C)c1=O
Formula: N/A
Pathway: Apoptosis
Target: BCL
Receptor: N/A
Bioactivity: BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 value of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity[1][2].
Molecular Weight: 484, 978
