Product Overview
BI-4924 | T14564 | TargetMol Chemicals
CAS: 2244452-09-1
Smiles: Cc1cc2n(C)c(cc2c(Cl)c1Cl)C(=O)N[C@H](CO)c1ccc(cc1)S(=O)(=O)CC(O)=O
Formula: C21H20Cl2N2O6S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: BI-4924 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM). It has excellent Microsomal and hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis at 72 h ( IC50: 2200 nM).
Molecular Weight: 499, 36
