Product Overview
BI-671800 | T14565 | TargetMol Chemicals
CAS: 1093108-50-9
Smiles: CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O
Formula: C25H26F3N5O3
Pathway: Endocrinology/Hormones|||GPCR/G Protein|||Immunology/Inflammation
Target: GPR|||Prostaglandin Receptor
Receptor: N/A
Bioactivity: BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma[2].
Molecular Weight: 501, 51
