Product Overview
BI-882370 | TQ0048 | TargetMol Chemicals
CAS: 1392429-79-6
Smiles: CCCS(=O)(=O)Nc1ccc(F)c(c1F)-n1cc(-c2cncnc2)c2nc(ccc12)N(C)C1CCN(CC)CC1
Formula: C28H33F2N7O2S
Pathway: MAPK
Target: Raf
Receptor: N/A
Bioactivity: BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.
Molecular Weight: 569, 68
