Bisdionin C | T40863

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TMC-T40863
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Product Overview

Bisdionin C | T40863 | TargetMol Chemicals

CAS: 74857-22-0

Smiles: Cn1cnc2n(C)c(=O)n(CCCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12

Formula: C17H20N8O4

Pathway: Microbiology/Virology

Target: Antibacterial

Receptor: N/A

Bioactivity: Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).

Molecular Weight: 400, 399

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