Product Overview
BMS-1 | T3655 | TargetMol Chemicals
CAS: 1675201-83-8
Smiles: COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O
Formula: C29H33NO5
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation
Target: Apoptosis|||PD-1/PD-L1
Receptor: N/A
Bioactivity: PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
Molecular Weight: 475, 585
