Product Overview
BMS-212122 | T30506 | TargetMol Chemicals
CAS: 194213-64-4
Smiles: Cc1nc2c(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)c(C)ccc2n1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc12
Formula: C43H36F6N4O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BMS-212122 is an effective microsomal triglyceride transfer protein inhibitor (MTP inhibitor). MS-212122 was more effective than BMS-201038 in lowering blood lipid (cholesterol, VLDL/LDL, TG) in hamsters and crab-eating monkeys. Treatment with BMS-212122 resulted in a rapid decrease in plasma lipid levels and a significant decrease in lipid content and mononuclear cell-derived (CD68+) cells in atherosclerotic plaques compared to baseline and diet-diet controls.
Molecular Weight: 754, 777
