BMS-248360 | T14672

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TMC-T14672
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Product Overview

BMS-248360 | T14672 | TargetMol Chemicals

CAS: 254737-87-6

Smiles: CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

Formula: C36H45N5O5S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor. With Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 shows hypertensive effects[1].

Molecular Weight: 659, 85

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