Product Overview
BMS-688521 | T14676 | TargetMol Chemicals
CAS: 893397-44-9
Smiles: ClC1=CC(Cl)=CC(N(C(N(C)[C@]23[C@H](C4=CC=C(C#N)C=C4)CN(C5=NC=C(C(O)=O)C=C5)C3)=O)C2=O)=C1
Formula: C26H19Cl2N5O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: BMS-688521 is efficacious in a mouse allergic eosinophilic lung inflammation model and it is a highly potent, orally active inhibitor of the LFA-1/ICAM interaction. With an IC50 of 2.5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay .
Molecular Weight: 536, 37
