Product Overview
BMS-695735 | T30538 | TargetMol Chemicals
CAS: 1054315-48-8
Smiles: Cc1cc(cc2nc([nH]c12)-c1c(NCCn2cc(Cl)cn2)cc[nH]c1=O)C1CCN(CCCF)CC1
Formula: C26H31ClFN7O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BMS-695735, a benzimidazole inhibitor of insulin-like growth factor-1 receptor, has broad-spectrum antitumor activity in vivo. It was found that BMS-695735 had strong inhibition of CYP3A4, induction of CYP3A4 mediated by PXR transactivation, poor water solubility, and high plasma protein binding.
Molecular Weight: 512, 03
