Product Overview
BMS-911543 | T6790 | TargetMol Chemicals
CAS: 1271022-90-2
Smiles: CCn1c(cc2c1nc(Nc1cc(C)n(C)n1)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1
Formula: C23H28N8O
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Tyrosine Kinases|||Histone Methyltransferase|||JAK
Receptor: N/A
Bioactivity: BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
Molecular Weight: 432, 532
