Product Overview
BMS-933043 | T26865 | TargetMol Chemicals
CAS: 1221973-93-8
Smiles: C1N=C(Nc2cc(ncn2)-n2ccnc2)O[C@]11CN2CCC1CC2
Formula: C16H19N7O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BMS-933043 is a Selective α7 nAChR partial agonist. BMS-933043 showed potent binding affinity to native rat (Ki = 3.3 nM) and recombinant human alpha7 nicotinic acetylcholine receptors (Ki = 8.1 nM). BMS-933043 shows agonist activity in a calcium fluorescence assay (EC50 = 23.4 nM) and whole cell voltage clamp electrophysiology (EC50 = 0.14 μM (rat) and 0.29 μM (human)).
Molecular Weight: 325, 376
