BMS-986169 | T23808

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TMC-T23808
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Product Overview

BMS-986169 | T23808 | TargetMol Chemicals

CAS: 1801151-08-5

Smiles: Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1

Formula: C23H27FN2O2

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: BMS-986169 is a GluN2B Receptor Negative Allosteric Modulator. BMS-986169 showed a high binding affinity for the GluN2B subunit allosteric modulatory site (Ki: 4.03-6.3 nM) and selectively inhibited GluN2B receptor function in Xenopus oocytes expressing human N-methyl-d-aspartate receptor subtypes (IC50: 24.1 nM).

Molecular Weight: 382, 479

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