BMS CCR2 22 | T14688

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TMC-T14688
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Product Overview

BMS CCR2 22 | T14688 | TargetMol Chemicals

CAS: 445479-97-0

Smiles: CSc1ccc(cc1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)CNC(=O)c1cc(ccc1NC(=O)NC(C)C)C(F)(F)F

Formula: C28H34F3N5O4S

Pathway: Immunology/Inflammation|||Microbiology/Virology

Target: CCR

Receptor: N/A

Bioactivity: BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist. It has excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM)[1][2].

Molecular Weight: 593, 67

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