Product Overview
BMX-IN-1 | T14692 | TargetMol Chemicals
CAS: 1431525-23-3
Smiles: Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1
Formula: C29H24N4O4S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: BTK
Receptor: N/A
Bioactivity: BMX-IN-1 is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
Molecular Weight: 524, 6