Boc-Pip-alkyne-Ph-COOH | T17689

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TMC-T17689
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Product Overview

Boc-Pip-alkyne-Ph-COOH | T17689 | TargetMol Chemicals

CAS: T17689

Smiles: OC(C1=CC=C(C#CC2CCN(C(OC(C)(C)C)=O)CC2)C=C1)=O

Formula: C19H23NO4

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266. ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM[1].

Molecular Weight: 329, 39

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