Product Overview
Bonducellin | TN5474 | TargetMol Chemicals
CAS: 83162-84-9
Smiles:
Formula: C17H14O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bonducellin shows weak antimalarial activity against Plasmodium falciparum with the IC50 value of 26 uM; it also shows weak antiproliferative against A2780 human ovarian cancer cell line, with the IC50 value of 10.6 uM. Bonducellin shows modulation in the MIC of EtBr by eight fold at a concentration of 62.5 mg/L and also shows significant efflux pump inhibitory activity.
Molecular Weight: N/A