Product Overview
BRD0476 | T26895 | TargetMol Chemicals
CAS: 1314958-91-2
Smiles: C[C@@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc3OCCOc3c2)Oc2c(NC(=O)Nc3cccc4ccccc34)cccc2C1=O
Formula: C35H38N4O8S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT signaling without suppressing the kinase activity of any JAK.
Molecular Weight: 674, 77