BRD5529 | T14777

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€100.00
SKU:
TMC-T14777
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Product Overview

BRD5529 | T14777 | TargetMol Chemicals

CAS: 1358488-78-4

Smiles: Cc1ccc(cc1)C(=O)Nc1cnc(N2CCC(CC2)(N2CCCCC2)C(N)=O)c(c1)C(O)=O

Formula: C25H31N5O4

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.

Molecular Weight: 465, 554

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