Product Overview
BRD5529 | T14777 | TargetMol Chemicals
CAS: 1358488-78-4
Smiles: Cc1ccc(cc1)C(=O)Nc1cnc(N2CCC(CC2)(N2CCCCC2)C(N)=O)c(c1)C(O)=O
Formula: C25H31N5O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.
Molecular Weight: 465, 554