Product Overview
Brilaroxazine | T14782 | TargetMol Chemicals
CAS: 1239729-06-6
Smiles: Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Formula: C22H25Cl2N3O3
Pathway: GPCR/G Protein|||Neuroscience
Target: Dopamine Receptor|||5-HT Receptor
Receptor: N/A
Bioactivity: Brilaroxazine is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-HT2B, and 5-HT7 receptors with Kis of 0.19 nM and 2.7 nM, respectively. Brilaroxazine can be used for research about cognitive impairments in neuropsychiatric and neurological diseases.
Molecular Weight: 450, 36