Product Overview
Brivanib (alaninate) | T2576 | TargetMol Chemicals
CAS: 649735-63-7
Smiles: Cc1cc2c(ccc(c2F)Oc2c3c(C)c(cn3ncn2)OC[C@@H](C)OC(=O)[C@H](C)N)[nH]1
Formula: C22H24FN5O4
Pathway: Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR|||Autophagy
Receptor: N/A
Bioactivity: Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.
Molecular Weight: 441, 46
