Product Overview
Brivanib | T6036 | TargetMol Chemicals
CAS: 649735-46-6
Smiles: C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C
Formula: C19H19FN4O3
Pathway: Angiogenesis|||Autophagy|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||VEGFR|||FGFR|||Autophagy
Receptor: N/A
Bioactivity: Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
Molecular Weight: 370, 38
