Product Overview
CAFESTOL | T5727 | TargetMol Chemicals
CAS: 469-83-0
Smiles: [H][C@]12CC[C@@]34C[C@@H](CC[C@@]3([H])[C@]1(C)CCc1occc21)[C@@](O)(CO)C4
Formula: C20H28O3
Pathway: Immunology/Inflammation|||MAPK|||Neuroscience|||NF-Κb
Target: ERK|||NF-κB|||COX|||PGE Synthase
Receptor: N/A
Bioactivity: CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.
Molecular Weight: 316, 441