Product Overview
CAL-101 | T8651 | TargetMol Chemicals
CAS: 1146702-54-6
Smiles: O=C1N(C2=CC=CC=C2)C([C@@H](NC3=C4N=CNC4=NC=N3)C)=NC5=C1C(F)=CC=C5
Formula: C22H18FN7O
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K
Receptor: N/A
Bioactivity: CAL-101 is a selective inhibitor of p110δ(IC50 : 2.5 nM; in cell-free assays); shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
Molecular Weight: 415, 42
