Canagliflozin hemihydrate | T1782L

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TMC-T1782L
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Product Overview

Canagliflozin hemihydrate | T1782L | TargetMol Chemicals

CAS: 928672-86-0

Smiles: O.Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Formula: C48H52F2O11S2

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Canagliflozin is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.

Molecular Weight: 907, 05

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