Product Overview
Capmatinib xHCl | T8416 | TargetMol Chemicals
CAS: 1029714-89-3
Smiles: Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
Formula: C23H18ClFN6O
Pathway: Tyrosine Kinase/Adaptors
Target: c-Met/HGFR
Receptor: N/A
Bioactivity: Capmatinib xHCl is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
Molecular Weight: 448, 89
