Product Overview
Capsazepine | T7177 | TargetMol Chemicals
CAS: 138977-28-3
Smiles: Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
Formula: C19H21ClN2O2S
Pathway: Apoptosis|||Membrane transporter/Ion channel
Target: Apoptosis|||TRP/TRPV Channel
Receptor: N/A
Bioactivity: Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is therefore considered to be a capsaicin antagonist.
Molecular Weight: 376, 9
