Product Overview
CAY10499 | T22637 | TargetMol Chemicals
CAS: T22637
Smiles: CC1=CC(N(N=C(O2)OC)C2=O)=CC=C1NC(OCC3=CC=CC=C3)=O
Formula: C18H17N3O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: CAY10499 is a potent inhibitor of monoglyceride lipase (MGL) and human hormone-sensitive lipase. CAY10499 inhibited MGL-mediated 4-NPA hydrolysis with the IC 50 value of 0.5 ± 0.03 μM. CAY10499 fully inhibited [3H]-AEA hydrolysis by human recombinant FAAH with an IC50 of 76 nM. CAY10499 displaced only 25% and 20% of [3H]-CP-55940-specific binding to the CB1 and CB2 receptors, respectively [1]. CAY10499 potently inhibited the activity of human hormone-sensitive lipase with an IC50 of 90 nM for the recombinant human hormone-sensitive lipase enzyme [1][2].
Molecular Weight: 355, 3
