Product Overview
CAY10566 | T14878 | TargetMol Chemicals
CAS: 944808-88-2
Smiles: Cc1nnc(o1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Cl
Formula: C18H17ClFN5O2
Pathway: Metabolism
Target: Dehydrogenase|||Stearoyl-CoA Desaturase (SCD)
Receptor: N/A
Bioactivity: CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..
Molecular Weight: 389, 82