Product Overview
CBL0137 hydrochloride | T4361 | TargetMol Chemicals
CAS: 1197397-89-9
Smiles: Cl.CC(C)NCCn1c2ccc(cc2c2cc(ccc12)C(C)=O)C(C)=O
Formula: C21H25ClN2O2
Pathway: Apoptosis|||NF-Κb|||Others
Target: Others|||NF-κB|||p53
Receptor: N/A
Bioactivity: CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.
Molecular Weight: 372, 89
