Product Overview
CCG-203971 | T4306 | TargetMol Chemicals
CAS: 1443437-74-8
Smiles: Clc1ccc(NC(=O)C2CCCN(C2)C(=O)c2cccc(c2)-c2ccco2)cc1
Formula: C23H21ClN2O3
Pathway: Cell Cycle/Checkpoint|||GPCR/G Protein|||MAPK
Target: Rho|||Ras
Receptor: N/A
Bioactivity: CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.
Molecular Weight: 408, 88
