CCR2 antagonist 4 hydrochloride | T19230

CCR2 antagonist 4 hydrochloride | T19230 | TargetMol Chemicals

CAS: 1313730-14-1

Smiles: Cl.FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1

Formula: C21H22Cl2F3N3O2

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).

Molecular Weight: 476, 32