CCR2 antagonist 4 | T13114

CCR2 antagonist 4 | T13114 | TargetMol Chemicals

CAS: 226226-39-7

Smiles: FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1

Formula: C21H21ClF3N3O2

Pathway: Immunology/Inflammation|||Microbiology/Virology|||Others

Target: Others|||CCR

Receptor: N/A

Bioactivity: CCR2 antagonist 4 is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).

Molecular Weight: 439, 86