Product Overview
CCT129202 | T6435 | TargetMol Chemicals
CAS: 942947-93-5
Smiles: CN(C)c1ccc(cc1)-c1nc2ncc(Cl)c(N3CCN(CC(=O)Nc4nccs4)CC3)c2[nH]1
Formula: C23H25ClN8OS
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Target: Aurora Kinase
Receptor: N/A
Bioactivity: CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
Molecular Weight: 497, 02