Product Overview
CCT241736 | T4428 | TargetMol Chemicals
CAS: 1402709-93-6
Smiles: Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1
Formula: C22H23Cl2N7
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Target: FLT|||Aurora Kinase
Receptor: N/A
Bioactivity: CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinical development candidate for the treatment of human malignancies, and in particular AML in adults and children.
Molecular Weight: 456, 38