Product Overview
CCT245737 | T7080 | TargetMol Chemicals
CAS: 1489389-18-5
Smiles: FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1
Formula: C16H16F3N7O
Pathway: Cell Cycle/Checkpoint
Target: Chk
Receptor: N/A
Bioactivity: CCT245737 is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).
Molecular Weight: 379, 347
